Literature summary for 2.7.8.8 extracted from

Chen, Y.L.; Montedonico, A.E.; Kauffman, S.; Dunlap, J.R.; Menn, F.M.; Reynolds, T.B.
Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence in Candida albicans (2010), Mol. Microbiol., 75, 1112-1132.

Search for more literature for 2.7.8.8

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Candida albicans	-	-	-

Synonyms

Synonyms	Comment	Organism
CHO1	-	Candida albicans
phosphatidylserine synthetase	-	Candida albicans
PS synthase	-	Candida albicans

General Information

General Information	Comment	Organism
malfunction	a phosphatidylserine synthase deletion mutant lacks phosphatidylserine, has decreased phosphatidylethanolamine, exhibits defects in cell wall integrity, mitochondrial function, filamentous growth, and is avirulent in a mouse model of systemic candidiasis	Candida albicans
physiological function	the enzyme is essential for cell wall integrity and virulence in Candida albicans	Candida albicans

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Release 2023.1 (January 2023)