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Literature summary for 2.7.8.7 extracted from

  • Leng, Y.; Zhong, S.
    Sfp-type 4'-phosphopantetheinyl transferase is required for lysine synthesis, tolerance to oxidative stress and virulence in the plant pathogenic fungus Cochliobolus sativus (2012), Mol. Plant Pathol., 13, 375-387.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
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Bipolaris sorokiniana 5739
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Organism

Organism UniProt Comment Textmining
Bipolaris sorokiniana G8DNT2 isolate ND90Pr (ATCC 201652)
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Synonyms

Synonyms Comment Organism
4'-phosphopantetheinyl transferase
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Bipolaris sorokiniana
PPT1
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Bipolaris sorokiniana
PPTase
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Bipolaris sorokiniana

Cofactor

Cofactor Comment Organism Structure
4'-phosphopantetheine
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Bipolaris sorokiniana

General Information

General Information Comment Organism
malfunction deletion of PPT1 generates mutants that are auxotrophic for lysine, unable to synthesize melanin, hypersensitive to iron and oxidative stress (H2O2) and significantly reduced in virulence to barley cultivar Bowman Bipolaris sorokiniana
physiological function Sfp-type 4-phosphopantetheinyl transferase is required for lysine synthesis, tolerance to oxidative stress and virulence of Cochliobolus sativus on barley cultivar Bowman. Isoform PPT1 is involved in conidiation, but does not affect the size, morphology and germination of conidia Bipolaris sorokiniana