Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Bipolaris sorokiniana | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bipolaris sorokiniana | G8DNT2 | isolate ND90Pr (ATCC 201652) | - |
Synonyms | Comment | Organism |
---|---|---|
4'-phosphopantetheinyl transferase | - |
Bipolaris sorokiniana |
PPT1 | - |
Bipolaris sorokiniana |
PPTase | - |
Bipolaris sorokiniana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
4'-phosphopantetheine | - |
Bipolaris sorokiniana |
General Information | Comment | Organism |
---|---|---|
malfunction | deletion of PPT1 generates mutants that are auxotrophic for lysine, unable to synthesize melanin, hypersensitive to iron and oxidative stress (H2O2) and significantly reduced in virulence to barley cultivar Bowman | Bipolaris sorokiniana |
physiological function | Sfp-type 4-phosphopantetheinyl transferase is required for lysine synthesis, tolerance to oxidative stress and virulence of Cochliobolus sativus on barley cultivar Bowman. Isoform PPT1 is involved in conidiation, but does not affect the size, morphology and germination of conidia | Bipolaris sorokiniana |