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Literature summary for 2.7.8.7 extracted from

  • Owen, J.G.; Robins, K.J.; Parachin, N.S.; Ackerley, D.F.
    A functional screen for recovery of 4'-phosphopantetheinyl transferase and associated natural product biosynthesis genes from metagenome libraries (2012), Environ. Microbiol., 14, 1198-1209.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CoA-[4'-phosphopantetheine] + apo-[BpsA protein]
-
Escherichia coli adenosine 3',5'-bisphosphate + holo-[BpsA protein]
-
?

Synonyms

Synonyms Comment Organism
4'-phosphopantetheinyl transferase
-
Escherichia coli
EntD
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Escherichia coli
PPTase
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Escherichia coli

Cofactor

Cofactor Comment Organism Structure
4'-phosphopantetheine
-
Escherichia coli

General Information

General Information Comment Organism
metabolism the enzyme is essential for activation of non-ribosomal peptide synthetase and polyketide synthase enzymes Escherichia coli