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Literature summary for 2.7.8.7 extracted from

  • Gaitatzis, N.; Hans, A.; Mueller, R.; Beyer, S.
    The mtaA gene of the myxothiazol biosynthetic gene cluster from Stigmatella aurantiaca DW4/3-1 encodes a phosphopantetheinyl transferase that activates polyketide synthases and polypeptide synthetases (2001), J. Biochem., 129, 119-124.
    View publication on PubMed
Search for more literature for 2.7.8.7

Application

Application Comment Organism
molecular biology MtaA should be a usefool tool for activating heterologously expressed polyketide synthase and nonribosomal polyketide synthase systems Stigmatella aurantiaca

Cloned(Commentary)

Cloned (Comment) Organism
mtaA gene of myxothiazol biosyntheic gene cluster, heterlogous coexpression with an acyl carrier protein domain in Escherichia coli XL1blue Stigmatella aurantiaca

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CoA + apo-[acyl-carrier protein] Stigmatella aurantiaca
-
 adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]
-
 r

Organism

Organism UniProt Comment Textmining
Stigmatella aurantiaca Q9RFL1 gene mtaA
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CoA + apo-[acyl-carrier protein]
-
 Stigmatella aurantiaca adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]
-
 r
additional information activates polyketide synthases and polypetide synthases, processes an aryl carrier protein domain ArCP, derived from the enterobactin synthetase of Escherichia coli, as well as a peptidyl carrier protein domain from a polypeptide synthase of yet unknown function from Sorangium cellulosum Stigmatella aurantiaca ?
-
 ?

Synonyms

Synonyms Comment Organism
4'-phosphopantetheinyl transferase
-
 Stigmatella aurantiaca
4'-PP transferase
-
 Stigmatella aurantiaca