Literature summary for 2.7.8.7 extracted from

Chirgadze, N.Y.; Briggs, S.L.; McAllister, K.A.; Fischl, A.S.; Zhao, G.
Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: an essential enzyme in bacterial fatty acid biosynthesis (2000), EMBO J., 19, 5281-5287.

Search for more literature for 2.7.8.7

Application

Application	Comment	Organism
medicine	enzyme plays an important role in bacterial fatty acid and lipid biosynthesis, making it an attractive target for therapeutic intervention, drug design by identifying inhibitors with potential antibacterial activity	Streptomyces pneumoniae

Cloned(Commentary)

Cloned (Comment)	Organism
sequenced	Streptomyces pneumoniae

Crystallization (Commentary)

Crystallization (Comment)	Organism
-	Streptomyces pneumoniae

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
CoA + apo-[acyl-carrier protein]	Streptomyces pneumoniae	transfer of acyl fatty acid intermediates during biosynthesis of fatty acids and lipids in the cell	adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]	-	r

Organism

Organism	UniProt	Comment	Textmining
Streptomyces pneumoniae	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CoA + apo-[acyl-carrier protein]	-	Streptomyces pneumoniae	adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]	-	r
CoA + apo-[acyl-carrier protein]	transfer of acyl fatty acid intermediates during biosynthesis of fatty acids and lipids in the cell	Streptomyces pneumoniae	adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]	-	r

Subunits

Subunits	Comment	Organism
trimer	-	Streptomyces pneumoniae

Synonyms

Synonyms	Comment	Organism
AcpS	-	Streptomyces pneumoniae

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Release 2023.1 (January 2023)