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Literature summary for 2.7.8.29 extracted from

  • Bergo, M.O.; Gavino, B.J.; Steenbergen, R.; Sturbois, B.; Parlow, A.F.; Sanan, D.A.; Skarnes, W.C.; Vance, J.E.; Young, S.G.
    Defining the importance of phosphatidylserine synthase 2 in mice (2002), J. Biol. Chem., 277, 47701-47708.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
brown fat high level of expression Mus musculus
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myometrium high level of expression Mus musculus
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neuron high level of expression Mus musculus
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Sertoli cell very high expression Mus musculus
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General Information

General Information Comment Organism
physiological function the ability of testis extracts from PSS2-deficient mice to catalyze serine exchange is reduced by more than 95%, reductions of 90% are found in the brain and liver. There are no perturbations in the phospholipid content of any of these tissues. The expression of PSS1, EC 2.7.8.8, is not upregulated in Pss2-deficient cells and tissues. Testis weight is reduced in Pss2-deficient mice, and some of the male mice are infertile Mus musculus