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Literature summary for 2.7.8.27 extracted from

  • Zhao, Y.R.; Dong, J.B.; Li, Y.; Wu, M.P.
    Sphingomyelin synthase 2 over-expression induces expression of aortic inflammatory biomarkers and decreases circulating EPCs in ApoE KO mice (2012), Life Sci., 90, 867-873.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Mus musculus (ApoE knockout mice) Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
SMS2
-
Homo sapiens
sphingomyelin synthase 2
-
Homo sapiens

General Information

General Information Comment Organism
physiological function isoform SMS2 over-expression is probably associated with increased expression of aortic inflammatory biomarkers, as well as decreased numbers of CD34/kinase-insert domain-positive cells, circulating angiogenic cells and colony-forming units in circulation. Therefore, SMS2 over-expression might correlate with endothelial dysfunction and aggravate atherosclerotic plaque instability in ApoE knockout mice Homo sapiens