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Literature summary for 2.7.8.24 extracted from
- Plant-exuded choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase (1999), J. Biol. Chem., 274, 20011-20016.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Triton X-100 | optimal activation at 0.2%, w/v | Sinorhizobium meliloti |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Triton X-100 | inhibitory at higher concentrations | Sinorhizobium meliloti | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | 20fold less effective than Mn2+ | Sinorhizobium meliloti | |
| Mn2+ | optimal activation at 10 mM, more effective than Mg2+ | Sinorhizobium meliloti | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-diacylglycerol + choline | Sinorhizobium meliloti | second bacterial pathway for phosphatidylcholine biosynthesis | CMP + phosphatidylcholine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sinorhizobium meliloti | - |
Rhizobium | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell culture | - |
Sinorhizobium meliloti | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-diacylglycerol + choline | second bacterial pathway for phosphatidylcholine biosynthesis | Sinorhizobium meliloti | CMP + phosphatidylcholine | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Sinorhizobium meliloti |
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