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Literature summary for 2.7.8.2 extracted from
- Formation of alkylacyl- and diacylglycerophosphocholines via diradylglycerol cholinephosphotransferase in rat liver (1982), Biochim. Biophys. Acta, 713, 479-483.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dithiothreitol | - |
Rattus norvegicus |  |
| ethanol | at high concentrations | Rattus norvegicus | |
| Mn2+ | 2 mM, 70-80% inhibition | Rattus norvegicus | |
| Tween-20 | at high concentrations | Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0143 | - |
1-hexadecanoyl-2-octadecanoyl-sn-glycerol | pH 8.2, 30°C | Rattus norvegicus | |
| 0.0262 | - |
1-hexadecyl-2-octadecenoyl-sn-glycerol | pH 8.2, 30°C | Rattus norvegicus | |
| 0.048 | - |
CDP-choline | cosubstrate 1-hexadecanoyl-2-octadecanoyl-sn-glycerol, pH 8.2, 30°C | Rattus norvegicus | |
| 0.053 | - |
CDP-choline | cosubstrate 1-hexadecyl-2-octadecenoyl-sn-glycerol, pH 8.2, 30°C | Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-choline + 1,2-diacylglycerol | - |
Rattus norvegicus | CMP + a phosphatidylcholine | - |
? | |
| CDP-choline + 1-hexadecanoyl-2-octadecanoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine | - |
? | |
| CDP-choline + 1-hexadecyl-2-octadecanoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-hexadecyl-2-octadecanoyl-sn-glycero-3-phosphocholine | - |
? | |
| CDP-choline + 1-hexadecyl-2-octadecenoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-hexadecyl-2-octadecenoyl-sn-glycero-3-phosphocholine | - |
? | |
| additional information | - |
Rattus norvegicus | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | 9 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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