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Literature summary for 2.7.8.19 extracted from

  • Hiller, A.M.; Koro, L.A.; Marchase, R.B.
    Glucose-1-phosphotransferase and N-acetylglucosamine-1-phosphotransferase have distinct acceptor specificities (1987), J. Biol. Chem., 262, 4377-4381.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information cathepsin D and beta-N-acetylhexosaminidase have no significant effects on phosphoglucose incorporation Gallus gallus
uteroferrin its inhibitory effect could be due to its phosphatase activity, and it is partially reduced by 0.001 mM molybdate Gallus gallus
uteroferrin
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Homo sapiens

Organism

Organism UniProt Comment Textmining
Gallus gallus
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-
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Homo sapiens
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-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast normal and I-cell Homo sapiens
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retina
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Gallus gallus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-glucose + glycoprotein D-mannose specific for UDP-glucose, endoglycosidase H-sensitive oligosaccharides on acceptor glycoproteins, primary acceptor in the chicken retina are peptides having apparent subunit MWs of 66000 and 62000 Gallus gallus UMP + glycoprotein 6-(D-glucose-1-phospho)-D-mannose
-
?
UDP-glucose + glycoprotein D-mannose specific for UDP-glucose, endoglycosidase H-sensitive oligosaccharides on acceptor glycoproteins, primary acceptor in the chicken retina are peptides having apparent subunit MWs of 66000 and 62000 Homo sapiens UMP + glycoprotein 6-(D-glucose-1-phospho)-D-mannose
-
?
UDP-glucose + glycoprotein D-mannose endogenous glycoprotein acceptor, the endogenous oligosaccharide acceptors for the GlcPTase are probably of high-mannose type, Glc-phosphotransferase may be involved in subcellular locallization of newly synthesized glycoproteins and its acceptors tagged by glucose 1-phosphate may comprise a particular group of glycoproteins destined for localization to the cell surface Gallus gallus UMP + glycoprotein 6-(D-glucose-1-phospho)-D-mannose
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?