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Literature summary for 2.7.8.17 extracted from

  • Kudo, M.; Canfield, W.M.
    Structural requirements for efficient processing and activation of recombinant human UDP-N-acetylglucosamine:lysosomal-enzyme-N-acetylglucosamine-1-phosphotransferase (2006), J. Biol. Chem., 281, 11761-11768.
    View publication on PubMed
Search for more literature for 2.7.8.17

Cloned(Commentary)

Cloned (Comment) Organism
expressed in CHO-K1 cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Homo sapiens 5783
-
Golgi apparatus
-
 Homo sapiens 5794
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
176000
-
 SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q3T906
-
-

Purification (Commentary)

Purification (Comment) Organism
HPC4-Sepharose column chromatography and DEAE-Sepharose column chromatography Homo sapiens

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.82
-
 after purification Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-glucosamine + methyl-alpha-D-mannoside
-
 Homo sapiens UMP + N-acetyl-D-glucosamine-phospho-(methyl-alpha-D-mannoside)
-
 ?

Subunits

Subunits Comment Organism
More multisubunit enzyme with an alpha2beta2gamma2 arrangement Homo sapiens

Synonyms

Synonyms Comment Organism
GlcNAc-phosphotransferase
-
 Homo sapiens
UDP-N-acetylglucosamine:lysosomal-enzyme-N-acetylglucosamine-1-phosphotransferase
-
 Homo sapiens