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Literature summary for 2.7.8.17 extracted from

  • Zhao, K.W.; Yeh, R.; Miller, A.L.
    Purification and characterization of human lymphoblast N-acetylglucosamine-1-phosphotransferase (1992), Glycobiology, 2, 119-125.
    View publication on PubMed
Search for more literature for 2.7.8.17

Activating Compound

Activating Compound Comment Organism Structure
Tergitol NP-10 required Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
phosphatidic acid
-
 Homo sapiens
phosphatidylglycerol
-
 Homo sapiens
phosphatidylserine
-
 Homo sapiens
UDP
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.024
-
 UDP-GlcNAc
-
 Homo sapiens
0.117
-
 methyl-alpha-D-mannoside
-
 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ divalent cation Mn2+ or Mg2+ is required Homo sapiens
Mn2+ divalent cation, Mn2+ or Mg2+ is required Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1000000
-
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lymphoblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-glucosamine + methyl-alpha-D-mannoside
-
 Homo sapiens UMP + N-acetyl-D-glucosamine-phospho-(methyl-alpha-D-mannoside)
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2 7.5
-
 Homo sapiens