Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Neutral lipid | stimulates synthesis of C55-isoprenyl-P-P-MurNAc-pentapeptide from UDPMurNAc-pentapeptide, no effect on exchange reaction of UDP-MurNAc-pentapeptide with UMP | Micrococcus luteus | |
Polar lipid fraction | required by exchange reaction of UDP-MurNAc-pentapeptide with UMP | Micrococcus luteus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Triton X-100 | activity is lost upon addition, can be restored by addition of lipid fractions to the assay | Micrococcus luteus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Micrococcus luteus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-NAc-muramoyl-pentapeptide + acceptor | Micrococcus luteus | - |
UMP + acceptor-phospho-NAc-muramoyl-pentapeptide | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Micrococcus luteus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-MurNAc-pentapeptide + C55-isoprenyl phosphate | - |
Micrococcus luteus | C55-isoprenyl-diphosphate-MurNAc-pentapeptide | - |
r | |
UDP-N-acetylmuramoyl-pentapeptide + [2H]UMP | - |
Micrococcus luteus | UMP + [2H]UDP-NAc-muramoyl-pentapeptide | - |
r | |
UDP-NAc-muramoyl-pentapeptide + acceptor | - |
Micrococcus luteus | UMP + acceptor-phospho-NAc-muramoyl-pentapeptide | - |
r |