General Stability | Organism |
---|---|
inactivation caused by repeated freezing and thawing or by contact with detergent is prevented by addition of dithiothreitol and CDPdiacyl-sn-glycerol | Rattus norvegicus |
loses activity when the lipids are removed | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bovine serum albumin | slight inhibition | Rattus norvegicus | |
cetyltrimethylammonium bromide | strong inhibition | Rattus norvegicus | |
iodoacetamide | - |
Rattus norvegicus | |
iodoacetate | - |
Rattus norvegicus | |
p-chloromercuribenzene sulfonate | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | membrane-bound | Rattus norvegicus | 16020 | - |
microsome | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
300000 | - |
partially purified enzyme, ultrafiltration | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CDP-diacylglycerol + myo-inositol | Rattus norvegicus | enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol | CMP + phosphatidyl-1D-myo-inositol | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
rat | - |
Purification (Comment) | Organism |
---|---|
partial | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | cerebral hemisphere | Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.233 | - |
- |
Rattus norvegicus |
Storage Stability | Organism |
---|---|
-20°C, substrate and dithioerythritol protects the enzyme activity for several days | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CDP-diacylglycerol + myo-inositol | - |
Rattus norvegicus | CMP + phosphatidyl-1D-myo-inositol | - |
r | |
CDP-diacylglycerol + myo-inositol | enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol | Rattus norvegicus | CMP + phosphatidyl-1D-myo-inositol | - |
r |