Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.7.8 extracted from

  • Wu, J.; Jiang, Z.; Liu, M.; Gong, X.; Wu, S.; Burns, C.M.; Li, Z.
    Polynucleotide phosphorylase protects Escherichia coli against oxidative stress (2009), Biochemistry, 48, 2012-2020.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.8

Organism

Organism UniProt Comment Textmining
Escherichia coli K-12
-
-
-
Escherichia coli K-12 CA244
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PNPase specifically binds a synthetic RNA containing the oxidative lesion 8-hydroxyguanine, PNPase binds to RNA molecules of natural sequence that are oxidatively damaged by treatment with hydrogen peroxide, PNPase binds oxidized RNA with higher affinity than untreated RNA of the same sequence Escherichia coli K-12 ?
-
 ?
additional information PNPase specifically binds a synthetic RNA containing the oxidative lesion 8-hydroxyguanine, PNPase binds to RNA molecules of natural sequence that are oxidatively damaged by treatment with hydrogen peroxide, PNPase binds oxidized RNA with higher affinity than untreated RNA of the same sequence Escherichia coli K-12 CA244 ?
-
 ?

Synonyms

Synonyms Comment Organism
PNPase
-
 Escherichia coli K-12
polynucleotide phosphorylase
-
 Escherichia coli K-12

General Information

General Information Comment Organism
malfunction PNPase-deficient mutant is hypersensitive to oxidative challenges Escherichia coli K-12
physiological function PNPase primarily functions in exonucleolytic degradation of RNA in the 3'->5' direction, PNPase also functions in minimizing oxidized RNA in vivo Escherichia coli K-12