Literature summary for 2.7.7.8 extracted from

Hayakawa, H.; Sekiguchi, M.
Human polynucleotide phosphorylase protein in response to oxidative stress (2006), Biochemistry, 45, 6749-6755.

Search for more literature for 2.7.7.8

Inhibitors

Inhibitors	Comment	Organism	Structure
hydrogen peroxide	upon exposure of human cells, the amount of enzyme protein decreases rapidly	Homo sapiens
menadione	upon exposure of human cells, the amount of enzyme protein decreases rapidly	Homo sapiens
additional information	no specific decrease in enzyme protein level upon treatment of cells with cycloheximide or ACNU, i.e. 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosurea hydrochloride	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	enzyme may play a role in excluding oxidized forms of RNA from the translation mechanism	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	enzyme may play a role in excluding oxidized forms of RNA from the translation mechanism	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)