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Literature summary for 2.7.7.76 extracted from
- Molybdopterin dinucleotide biosynthesis in Escherichia coli: Identification of amino acid residues of molybdopterin dinucleotide transferases that determine specificity for binding of guanine or cytosine nucleotides (2011), J. Biol. Chem., 286, 1400-1408.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| L79P/T81A/S82G | increased Km for CTP, decreased kcat | Escherichia coli |
| T9L/A11G | increased Km for CTP, decreased kcat | Escherichia coli |
| T9L/A11G/L79P/T81A/S82G | increased Km for CTP, decreased kcat, low activity with GTP instead of CTP | Escherichia coli |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Escherichia coli |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CTP + molybdenum cofactor | Escherichia coli | - |
diphosphate + cytidylyl molybdenum cofactor | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
K-12 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CTP + molybdenum cofactor | - |
Escherichia coli | diphosphate + cytidylyl molybdenum cofactor | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MocA | - |
Escherichia coli |
| YgfJ | - |
Escherichia coli |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | molybdenum cofactor biosynthesis | Escherichia coli |
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Release 2023.1 (January 2023)
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