Literature summary for 2.7.7.7 extracted from

Irimia, A.; Eoff, R.L.; Pallan, P.S.; Guengerich, F.P.; Egli, M.
Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene (2007), J. Biol. Chem., 282, 36421-36433.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
crystal structures of Dpo4 in complex with DNA duplexes containing the 2,4-difluorotoluene analog. The structures provide insight into the discrimination by Dpo4 between dATP and dGTP opposite 2,4-difluorotoluene and its inability to extend beyond a G:2,4-difluorotoluene pair	Saccharolobus solfataricus

Organism

Organism	UniProt	Comment	Textmining
Saccharolobus solfataricus	Q97W02	-	-
Saccharolobus solfataricus P2	Q97W02	-	-

Synonyms

Synonyms	Comment	Organism
DNA polymerase Dpo4	-	Saccharolobus solfataricus

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Release 2023.1 (January 2023)