Literature summary for 2.7.7.7 extracted from

Salas, M.; Blanco, L.; Lazaro, J.; de Vega, M.
The bacteriophage phi29 DNA polymerase (2008), IUBMB Life, 60, 82-85.

Search for more literature for 2.7.7.7

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
66000	-	-	Salasvirus phi29

Organism

Organism	UniProt	Comment	Textmining
Salasvirus phi29	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
deoxynucleoside triphosphate + DNAn	phi29 DNA polymerase accomplishes sequential template-directed addition of dNMP units onto the 3'-OH group of a growing DNA chain, in addition phi29 DNApol catalyses 3'-5' exonucleolysis, that is, the release of dNMP units from the 3' end of a DNA strand	Salasvirus phi29	diphosphate + DNAn+1	-	?

Subunits

Subunits	Comment	Organism
monomer	1 * 66000, gel filtration	Salasvirus phi29

Synonyms

Synonyms	Comment	Organism
phi29 DNA polymerase	phi29 DNApol is included in the B family (eukaryotic-type) of DNA-dependent DNA polymerases	Salasvirus phi29
phi29 DNApol	-	Salasvirus phi29

General Information

General Information	Comment	Organism
physiological function	phi29 DNA polymerase is fully responsible for viral DNA replication	Salasvirus phi29

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Release 2023.1 (January 2023)