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Literature summary for 2.7.7.7 extracted from

  • Doncaster, J.R.; Etchells, L.L.; Kershaw, N.M.; Nakamura, R.; Ryan, H.; Takeuchi, R.; Sakaguchi, K.; Sardarian, A.; Whitehead, R.C.
    Synthetic analogues of the manzamenones and plakoridines which inhibit DNA polymerase (2006), Bioorg. Med. Chem. Lett., 16, 2877-2881.
    View publication on PubMed
Search for more literature for 2.7.7.7

Inhibitors

Inhibitors Comment Organism Structure
(E)-enedione
-
 Homo sapiens
plakevulin A
-
 Homo sapiens
untenone A
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
DNA polymerase alpha
-
 Homo sapiens
DNA polymerase beta
-
 Homo sapiens
pol alpha
-
 Homo sapiens
pol beta
-
 Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0037
-
-
 Homo sapiens (E)-enedione
0.0043
-
-
 Homo sapiens untenone A
0.0088
-
-
 Homo sapiens (E)-enedione
0.057
-
-
 Homo sapiens untenone A
0.066
-
-
 Homo sapiens plakevulin A
0.179
-
-
 Homo sapiens plakevulin A