Literature summary for 2.7.7.7 extracted from

Yomo, T.; Hatanaka, T.; Yamamoto, H.; Yamamoto, K.; Shima, Y.; Ko-Mitamura, E.P.; Urabe, I.
Kinetic equation for template-dependent polymerase reactions and its application to Thermus thermophilus DNA polymerase (1998), J. Ferment. Bioeng., 86, 379-384.

No PubMed abstract available

Search for more literature for 2.7.7.7

Application

Application	Comment	Organism
biotechnology	thermostable polymerase used in PCR	Thermus thermophilus
molecular biology	thermostable polymerase used in PCR	Thermus thermophilus

Inhibitors

Inhibitors	Comment	Organism	Structure
deoxynucleoside triphosphate	work as competitive inhibitors depending on their incorporation sites, A-incorporation is strongly inhibited by dTTP and dGTP, T-incorporation is inhibited by dATP, G-and C-incorporation sites are less sensitive to competitive inhibition	Thermus thermophilus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
deoxynucleoside triphosphate + DNAn	Thermus thermophilus	-	diphosphate + DNAn+1	-	?

Organism

Organism	UniProt	Comment	Textmining
Thermus thermophilus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
deoxynucleoside triphosphate + DNAn	-	Thermus thermophilus	diphosphate + DNAn+1	-	?

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Release 2023.1 (January 2023)