Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.7.7 extracted from

  • Aoyagi, N.; Matsuoka, S.; Furunobu, A; Matsukage, A.; Sakaguchi, K.
    Drosophila DNA polymerase delta. Purification and characterization (1994), J. Biol. Chem., 169, 6045-5050.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
proliferating cell nuclear antigen
-
Drosophila melanogaster

Inhibitors

Inhibitors Comment Organism Structure
aphidicolin
-
Drosophila melanogaster
KCl
-
Drosophila melanogaster
N-ethylmaleimide
-
Drosophila melanogaster

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Drosophila melanogaster

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
47000
-
1 * 138000 + 1 * 47000, SDS-PAGE Drosophila melanogaster
138000
-
1 * 138000 + 1 * 47000, SDS-PAGE Drosophila melanogaster
185000
-
gel filtration Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
deoxynucleoside triphosphate + DNAn Drosophila melanogaster
-
diphosphate + DNAn+1
-
?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Purification (Commentary)

Purification (Comment) Organism
near homogeneity Drosophila melanogaster

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
Drosophila melanogaster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn
-
Drosophila melanogaster diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn exonuclease 3'--5' activity Drosophila melanogaster diphosphate + DNAn+1
-
?

Subunits

Subunits Comment Organism
dimer 1 * 138000 + 1 * 47000, SDS-PAGE Drosophila melanogaster

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
-
Drosophila melanogaster

pI Value

Organism Comment pI Value Maximum pI Value
Drosophila melanogaster
-
-
6.8