Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.7.65 extracted from

  • Dahlstrom, K.M.; O'Toole, G.A.
    A symphony of cyclases specificity in diguanylate cyclase signaling (2017), Annu. Rev. Microbiol., 71, 179-195 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.65

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 GTP Pseudomonas aeruginosa
-
 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP Caulobacter vibrioides
-
 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP Vibrio cholerae serotype O1
-
 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP Clostridioides difficile
-
 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP Burkholderia cenocepacia
-
 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP Escherichia coli
-
 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP Komagataeibacter xylinus
-
 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP Vibrio cholerae serotype O1 A1552
-
 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?

Organism

Organism UniProt Comment Textmining
Burkholderia cenocepacia
-
-
-
Caulobacter vibrioides
-
-
-
Clostridioides difficile
-
-
-
Escherichia coli P0AA89
-
-
Komagataeibacter xylinus O87374 DGC1
-
Pseudomonas aeruginosa
-
-
-
Vibrio cholerae serotype O1
-
-
-
Vibrio cholerae serotype O1 A1552
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 GTP
-
 Pseudomonas aeruginosa 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP
-
 Caulobacter vibrioides 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP
-
 Vibrio cholerae serotype O1 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP
-
 Clostridioides difficile 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP
-
 Burkholderia cenocepacia 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP
-
 Escherichia coli 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP
-
 Komagataeibacter xylinus 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
2 GTP
-
 Vibrio cholerae serotype O1 A1552 2 diphosphate + cyclic di-3',5'-guanylate
-
 ?
additional information analysis of the DGC specificity, overview Pseudomonas aeruginosa ?
-
-
additional information analysis of the DGC specificity, overview Caulobacter vibrioides ?
-
-
additional information analysis of the DGC specificity, overview Vibrio cholerae serotype O1 ?
-
-
additional information analysis of the DGC specificity, overview Clostridioides difficile ?
-
-
additional information analysis of the DGC specificity, overview Burkholderia cenocepacia ?
-
-
additional information analysis of the DGC specificity, overview Escherichia coli ?
-
-
additional information analysis of the DGC specificity, overview Komagataeibacter xylinus ?
-
-
additional information analysis of the DGC specificity, overview Vibrio cholerae serotype O1 A1552 ?
-
-

Synonyms

Synonyms Comment Organism
cdgJ
-
 Vibrio cholerae serotype O1
DGC
-
 Pseudomonas aeruginosa
DGC
-
 Caulobacter vibrioides
DGC
-
 Vibrio cholerae serotype O1
DGC
-
 Clostridioides difficile
DGC
-
 Burkholderia cenocepacia
DGC
-
 Escherichia coli
DGC
-
 Komagataeibacter xylinus
Dgc1
-
 Pseudomonas aeruginosa
Dgc1
-
 Caulobacter vibrioides
Dgc1
-
 Clostridioides difficile
Dgc1
-
 Burkholderia cenocepacia
Dgc1
-
 Komagataeibacter xylinus
DosC
-
 Escherichia coli

General Information

General Information Comment Organism
metabolism cyclic diguanylate (c-di-GMP) is a near universal signaling molecule produced by diguanylate cyclases that can direct a variety of bacterial behaviors. Effectors, e.g. LapD, can sense the c-di-GMP signal from a specific DGC. Relationship between DGC-effector contact and catalysis. Dynamics of a signaling complex, distinguishing interaction versus signaling, and relationship between local and global signaling, overview. Modeling Pseudomonas aeruginosa
metabolism cyclic diguanylate (c-di-GMP) is a near universal signaling molecule produced by diguanylate cyclases that can direct a variety of bacterial behaviors. Effectors, e.g. LapD, can sense the c-di-GMP signal from a specific DGC. Relationship between DGC-effector contact and catalysis. Dynamics of a signaling complex, distinguishing interaction versus signaling, and relationship between local and global signaling, overview. Modeling Caulobacter vibrioides
metabolism cyclic diguanylate (c-di-GMP) is a near universal signaling molecule produced by diguanylate cyclases that can direct a variety of bacterial behaviors. Effectors, e.g. LapD, can sense the c-di-GMP signal from a specific DGC. Relationship between DGC-effector contact and catalysis. Dynamics of a signaling complex, distinguishing interaction versus signaling, and relationship between local and global signaling, overview. Modeling Vibrio cholerae serotype O1
metabolism cyclic diguanylate (c-di-GMP) is a near universal signaling molecule produced by diguanylate cyclases that can direct a variety of bacterial behaviors. Effectors, e.g. LapD, can sense the c-di-GMP signal from a specific DGC. Relationship between DGC-effector contact and catalysis. Dynamics of a signaling complex, distinguishing interaction versus signaling, and relationship between local and global signaling, overview. Modeling Clostridioides difficile
metabolism cyclic diguanylate (c-di-GMP) is a near universal signaling molecule produced by diguanylate cyclases that can direct a variety of bacterial behaviors. Effectors, e.g. LapD, can sense the c-di-GMP signal from a specific DGC. Relationship between DGC-effector contact and catalysis. Dynamics of a signaling complex, distinguishing interaction versus signaling, and relationship between local and global signaling, overview. Modeling Burkholderia cenocepacia
metabolism cyclic diguanylate (c-di-GMP) is a near universal signaling molecule produced by diguanylate cyclases that can direct a variety of bacterial behaviors. Effectors, e.g. LapD, can sense the c-di-GMP signal from a specific DGC. Relationship between DGC-effector contact and catalysis. Dynamics of a signaling complex, distinguishing interaction versus signaling, and relationship between local and global signaling, overview. Modeling Escherichia coli
metabolism cyclic diguanylate (c-di-GMP) is a near universal signaling molecule produced by diguanylate cyclases that can direct a variety of bacterial behaviors. Effectors, e.g. LapD, can sense the c-di-GMP signal from a specific DGC. Relationship between DGC-effector contact and catalysis. Dynamics of a signaling complex, distinguishing interaction versus signaling, and relationship between local and global signaling, overview. Modeling Komagataeibacter xylinus
additional information DGCs operate as dimers, using their GGDEF domains to produce c-di-GMP. In addition to GGDEF, active cyclases have also been found that make use of GGEEF, AGDEF, and GGDEM motifs Pseudomonas aeruginosa
additional information DGCs operate as dimers, using their GGDEF domains to produce c-di-GMP. In addition to GGDEF, active cyclases have also been found that make use of GGEEF, AGDEF, and GGDEM motifs Caulobacter vibrioides
additional information DGCs operate as dimers, using their GGDEF domains to produce c-di-GMP. In addition to GGDEF, active cyclases have also been found that make use of GGEEF, AGDEF, and GGDEM motifs Vibrio cholerae serotype O1
additional information DGCs operate as dimers, using their GGDEF domains to produce c-di-GMP. In addition to GGDEF, active cyclases have also been found that make use of GGEEF, AGDEF, and GGDEM motifs Clostridioides difficile
additional information DGCs operate as dimers, using their GGDEF domains to produce c-di-GMP. In addition to GGDEF, active cyclases have also been found that make use of GGEEF, AGDEF, and GGDEM motifs Burkholderia cenocepacia
additional information DGCs operate as dimers, using their GGDEF domains to produce c-di-GMP. In addition to GGDEF, active cyclases have also been found that make use of GGEEF, AGDEF, and GGDEM motifs Escherichia coli
additional information DGCs operate as dimers, using their GGDEF domains to produce c-di-GMP. In addition to GGDEF, active cyclases have also been found that make use of GGEEF, AGDEF, and GGDEM motifs Komagataeibacter xylinus