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Literature summary for 2.7.7.62 extracted from

  • Warren, M.J.; Raux, E.; Schubert, H.L.; Escalante-Semerena, J.C.
    The biosynthesis of adenosylcobalamin (vitamin B12) (2002), Nat. Prod. Rep., 19, 390-412.
    View publication on PubMed
Search for more literature for 2.7.7.62

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Salmonella enterica

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
20000
-
 amino acid sequence, small polypeptide with 180 amino acids Salmonella enterica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + adenosylcobinamide phosphate Escherichia coli cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate Methanothermobacter thermautotrophicus cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate Priestia megaterium cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate Pseudomonas denitrificans (nom. rej.) cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate Propionibacterium freudenreichii cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate Salmonella enterica cobalamin biosynthesis, involved in de novo synthesis of vitamin B12, uses GTP to guanylate itself, then transfers this GMP group to AdoCbi-P to yield AdoCbi-GDP, the final product of the reaction diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate Methanothermobacter thermautotrophicus DELTAH cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 diphosphate + adenosylcobinamide-GDP
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Methanothermobacter thermautotrophicus
-
-
-
Methanothermobacter thermautotrophicus DELTAH
-
-
-
Priestia megaterium
-
-
-
Propionibacterium freudenreichii
-
 formerly Propionibacterium shermanii
-
Pseudomonas denitrificans (nom. rej.)
-
-
-
Salmonella enterica
-
 serovar typhimurium
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + adenosylcobinamide phosphate
-
 Escherichia coli diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate
-
 Methanothermobacter thermautotrophicus diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate
-
 Priestia megaterium diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate
-
 Pseudomonas denitrificans (nom. rej.) diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate
-
 Salmonella enterica diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate
-
 Propionibacterium freudenreichii diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 Escherichia coli diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 Methanothermobacter thermautotrophicus diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 Priestia megaterium diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 Pseudomonas denitrificans (nom. rej.) diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 Propionibacterium freudenreichii diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate cobalamin biosynthesis, involved in de novo synthesis of vitamin B12, uses GTP to guanylate itself, then transfers this GMP group to AdoCbi-P to yield AdoCbi-GDP, the final product of the reaction Salmonella enterica diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate
-
 Methanothermobacter thermautotrophicus DELTAH diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 Methanothermobacter thermautotrophicus DELTAH diphosphate + adenosylcobinamide-GDP
-
 ?
additional information CobU is a bifunctional enzyme that has both kinase EC 2.7.1.156 and guanyltransferase EC 2.7.7.62 activities Escherichia coli ?
-
 ?
additional information CobU is a bifunctional enzyme that has both kinase EC 2.7.1.156 and guanyltransferase EC 2.7.7.62 activities Priestia megaterium ?
-
 ?
additional information CobU is a bifunctional enzyme that has both kinase EC 2.7.1.156 and guanyltransferase EC 2.7.7.62 activities Pseudomonas denitrificans (nom. rej.) ?
-
 ?
additional information CobU is a bifunctional enzyme that has both kinase EC 2.7.1.156 and guanyltransferase EC 2.7.7.62 activities Salmonella enterica ?
-
 ?
additional information CobU is a bifunctional enzyme that has both kinase EC 2.7.1.156 and guanyltransferase EC 2.7.7.62 activities Propionibacterium freudenreichii ?
-
 ?
additional information CobU is a bifunctional enzyme that has both kinase EC 2.7.1.156 and guanyltransferase EC 2.7.7.62 activities, cobY gene encodes a protein with GTP:AdoCbi-P guanyltransferase activity but no NTP:AdoCbi kinase activity Methanothermobacter thermautotrophicus ?
-
 ?
additional information CobU is a bifunctional enzyme that has both kinase EC 2.7.1.156 and guanyltransferase EC 2.7.7.62 activities, cobY gene encodes a protein with GTP:AdoCbi-P guanyltransferase activity but no NTP:AdoCbi kinase activity Methanothermobacter thermautotrophicus DELTAH ?
-
 ?

Subunits

Subunits Comment Organism
trimer
-
 Salmonella enterica

Synonyms

Synonyms Comment Organism
adenosylcobinamide guanylyltransferase
-
 Salmonella enterica
adenosylcobinamide kinase
-
 Escherichia coli
adenosylcobinamide kinase
-
 Priestia megaterium
adenosylcobinamide kinase
-
 Propionibacterium freudenreichii
adenosylcobinamide phosphate guanylyltransferase
-
 Pseudomonas denitrificans (nom. rej.)
CobU
-
 Escherichia coli
CobU
-
 Priestia megaterium
CobU
-
 Pseudomonas denitrificans (nom. rej.)
CobU
-
 Salmonella enterica
CobU
-
 Propionibacterium freudenreichii
guanyltransferase
-
 Methanothermobacter thermautotrophicus