Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Mus musculus | 5634 | - |
nucleus | - |
Homo sapiens | 5634 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Mus musculus | |
Mg2+ | required | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
nucleoside triphosphate + RNAn | Mus musculus | - |
diphosphate + RNAn+1 | - |
? | |
nucleoside triphosphate + RNAn | Homo sapiens | - |
diphosphate + RNAn+1 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | the three subunits are simultaneously glycosylated in vivo by O-N-acetylglucosamine residues, glycosylation and phosphorylation of the three subunits is dynamic and differs between the subunits, , also depending on the physiological state of the cell, overview | Homo sapiens |
glycoprotein | the two subunits are simultaneously glycosylated by N-O-acetylglucosamine residues in vivo, glycosylation and phosphorylation of the two subunits is dynamic and differs between the subunits, , also depending on the physiological state of the cell, overview | Mus musculus |
phosphoprotein | the three subunits are simultaneously phosphorylated on serine and threonine residues in vivo, glycosylation and phosphorylation of the three subunits is dynamic and differs between the subunits, , also depending on the physiological state of the cell, overview | Homo sapiens |
phosphoprotein | the two subunits are simultaneously phosphorylated on serine and threonine residues in vivo, glycosylation and phosphorylation of the three subunits is dynamic and differs between the subunits, also depending on the physiological state of the cell, overview | Mus musculus |
Purification (Comment) | Organism |
---|---|
RNA polymerase III subunits isolation from A-431 cells and placenta cell nuclei by anion exchange chromatography and ultrafiltration | Homo sapiens |
RNA polymerase III subunits isolation from fibroblast nuclei by anion exchange chromatography and ultrafiltration | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
3T3 cell | - |
Mus musculus | - |
A-431 cell | - |
Homo sapiens | - |
epidermoid carcinoma cell | - |
Homo sapiens | - |
fibroblast | - |
Mus musculus | - |
placenta | mature | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nucleoside triphosphate + RNAn | - |
Mus musculus | diphosphate + RNAn+1 | - |
? | |
nucleoside triphosphate + RNAn | - |
Homo sapiens | diphosphate + RNAn+1 | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | subunits with molecular weights of 49 kDa and 42 kDa and a subunit with a molecular weight of 45 kDa (which is probably a component of the basal transcription factor of RNA polymerase III, since it is not identified in the mouse enzyme) are modified in the composition of the enzyme isolated from mouse fibroblasts. The two subunits are simultaneously phosphorylated and glycosylated (glycosylation by O-N-acetylglucosamine residues) | Mus musculus |
More | subunits with molecular weights of 60 kDa and 45 kDa and a subunit with a molecular weight of 52 kDa (which is probably one of the basal transcription factors of RNA polymerase III) are modified in the composition of the enzyme isolated from human cells. The three subunits are simultaneously phosphorylated and glycosylated | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
RNA polymerase III | - |
Mus musculus |
RNA polymerase III | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.9 | - |
assay at | Mus musculus |
7.9 | - |
assay at | Homo sapiens |