Inhibitors | Comment | Organism | Structure |
---|---|---|---|
B2 RNA | the about 180-nt B2 RNA potently represses mRNA transcription by binding tightly to RNA polymerase II and assembling with it into complexes on promoter DNA, where it keeps the polymerase from properly engaging the promoter DNA. The C-terminal domain of the largest Pol II subunit is not involved. B2 RNA binds Pol II and assembles into complexes at promoters. Binding site anaylsis usig Pol II peptides, binding structure, and mechanism of transcriptional repression by B2 RNA, detailed overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the B2 family of short interspersed elements is transcribed into non-coding RNA by RNA polymerase III | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the B2 family of short interspersed elements is transcribed into non-coding RNA by RNA polymerase III | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Pol II | - |
Homo sapiens |
RNA polymerase II | - |
Homo sapiens |
RNA polymerase III | - |
Homo sapiens |