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Literature summary for 2.7.7.6 extracted from
- Non-DNA-templated addition of nucleotides to the 3' end of RNAs by the mitochondrial RNA polymerase of Physarum polycephalum (2008), Mol. Cell. Biol., 28, 5795-5802.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cloning of the cDNA for the mtRNAP of Physarum and expression in Escherichia coli | Physarum polycephalum |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | the enzyme in nucleus encoded and then transported to the mitochondrion | Physarum polycephalum | 5739 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| nucleoside triphosphate + RNAn | Physarum polycephalum | - |
diphosphate + RNAn+1 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Physarum polycephalum | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | identification of an activity associated with the mtRNAP in which non-DNA-templated nucleotides are added to the 3' end of RNAs, any of the four rNTPs can act as precursors for this process, RNA editing mechanism, overview. Nucleotides that are not specified by the mitochondrial DNA templates are inserted into some RNAs, a process called RNA editing. This is an essential step in the expression of these RNAs, as the insertion of the nontemplated nucleotides creates open reading frames for the production of proteins from mRNAs or produces required secondary structure in rRNAs and tRNAs | Physarum polycephalum | ? | - |
? | |
| nucleoside triphosphate + RNAn | - |
Physarum polycephalum | diphosphate + RNAn+1 | - |
? | |
| nucleoside triphosphate + RNAn | supercoiled, double-stranded DNA template is more efficient than that from nonsupercoiled DNA, in vitro transcription activity and mechanism, overview | Physarum polycephalum | diphosphate + RNAn+1 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| mitochondrial RNA polymerase | - |
Physarum polycephalum |
| mtRNAP | - |
Physarum polycephalum |
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