Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.7.6 extracted from

  • Sethi, V.S.
    Structure and function of DNA-dependent RNA-polymerase (1971), Prog. Biophys. Mol. Biol., 23, 67-101.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1-[2-[3-(4-Chloro-3-trifluoromethylphenyl)ureido]-4-trifluoromethyl phenoxy]-4,5-dichlorobenzene sulfonic acid
-
Escherichia coli
actinomycin
-
Escherichia coli
amanitin
-
Escherichia coli
aureolic acid
-
Escherichia coli
chromomycin
-
Escherichia coli
Cinerubin B
-
Escherichia coli
Cordycepin triphosphate
-
Escherichia coli
daunomycin
-
Escherichia coli
echinomycin
-
Escherichia coli
Eruticulomycin A
-
Escherichia coli
Ethidium bromide
-
Escherichia coli
Exotoxin of Bacillus thuringiensis
-
Escherichia coli
heparin
-
Escherichia coli
Isoquinocyclin
-
Escherichia coli
Nogalamycin
-
Escherichia coli
Olivomycin
-
Escherichia coli
proflavin sulfate
-
Escherichia coli
rifampicin
-
Escherichia coli
Streptolydigin
-
Escherichia coli
streptovaricin
-
Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
beta‘x,beta,sigma,alpha, x * 160000 + x * 145000 + x * 85000 + x * 40000, SDS-PAGE Escherichia coli
85000
-
beta‘x,beta,sigma,alpha, x * 160000 + x * 145000 + x * 85000 + x * 40000, SDS-PAGE Escherichia coli
145000
-
beta‘x,beta,sigma,alpha, x * 160000 + x * 145000 + x * 85000 + x * 40000, SDS-PAGE Escherichia coli
160000
-
beta‘x,beta,sigma,alpha, x * 160000 + x * 145000 + x * 85000 + x * 40000, SDS-PAGE Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside triphosphate + RNAn the enzyme requires DNA as template Escherichia coli diphosphate + RNAn+1
-
?

Subunits

Subunits Comment Organism
? beta‘x,beta,sigma,alpha, x * 160000 + x * 145000 + x * 85000 + x * 40000, SDS-PAGE Escherichia coli
More dimer-monomer formation is reversible and the equilibrium depends on the ionic strength of the medium. At high ionic strength the enzyme dissociates to a monomeric form Escherichia coli