Any feedback?
Literature summary for 2.7.7.53 extracted from
- Diadenosine 5,5-P1, P4-tetraphosphate alpha, beta-phosphorylase from yeast supports nucleoside diphosphate-phosphate exchange (1986), J. Biol. Chem., 261, 5943-5946.
General Stability
| General Stability | Organism |
|---|---|
| dithioerythritol stabilizes | Saccharomyces cerevisiae |
| glycerol, 10%, stabilizes | Saccharomyces cerevisiae |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| AMP | ADP/phosphate-exchange | Saccharomyces cerevisiae |  |
| Ap3A | ADP/phosphate-exchange | Saccharomyces cerevisiae | |
| Ca2+ | weak, NDP-arsenolysis or NDP/phosphate-exchange reaction | Saccharomyces cerevisiae | |
| Cd2+ | only NDP-arsenolysis or NDP/phosphate-exchange reaction | Saccharomyces cerevisiae | |
| Co2+ | weak, NDP-arsenolysis or NDP/phosphate-exchange reaction | Saccharomyces cerevisiae | |
| Mg2+ | only NDP-arsenolysis or NDP/phosphate-exchange reaction | Saccharomyces cerevisiae | |
| Mn2+ | weak, NDP-arsenolysis or NDP/phosphate-exchange reaction | Saccharomyces cerevisiae | |
| P1,P4-bis(5'-adenosyl) tetraphosphate | ADP/phosphate-exchange | Saccharomyces cerevisiae | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | exchange reaction with ADP and analogues | Saccharomyces cerevisiae | |
| 0.7 | - |
ADP | ADP/phosphate-exchange, pH 7.0, 37°C | Saccharomyces cerevisiae | |
| 0.7 | - |
GDP | ADP/phosphate-exchange, pH 7.0, 37°C | Saccharomyces cerevisiae | |
| 2 | - |
phosphate | ADP/phosphate-exchange, pH 7.0, 37°C | Saccharomyces cerevisiae | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | not NDP-arsenolysis or NDP/phosphate-exchange reaction | Saccharomyces cerevisiae | |
| additional information | no divalent metal cation requirement for NDP-arsenolysis or NDP/phosphate-exchange reaction | Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | broad substrate specificity | Saccharomyces cerevisiae | ? | - |
? | |
| NDP + arsenate | - |
Saccharomyces cerevisiae | NMP + phosphate + ? | - |
? | |
| NDP + phosphate | exchange reaction between beta-phosphate of NDP and phosphate from the medium | Saccharomyces cerevisiae | phosphate + NDP | - |
r | |
| P1,P4-bis(5'-adenosyl) tetraphosphate + phosphate | - |
Saccharomyces cerevisiae | ADP + ATP | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Saccharomyces cerevisiae |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 96 | - |
ADP | ADP/phosphate-exchange, pH 7.0, 37°C | Saccharomyces cerevisiae | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| additional information | - |
pH-dependence of NDP/phosphate-exchange reaction | Saccharomyces cerevisiae |
| 6.5 | - |
UDP + phosphate, NDP/phosphate-exchange, ADP, GDP or CDP + arsenate, NDP-arsenolysis | Saccharomyces cerevisiae |
| 7 | - |
ADP or CDP + phosphate, NDP/phosphate-exchange | Saccharomyces cerevisiae |
| 8 | - |
GDP + phosphate, NDP/phosphate-exchange | Saccharomyces cerevisiae |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
