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Literature summary for 2.7.7.50 extracted from

  • Martin, S.A.; Moss, B.
    mRNA guanylyltransferase and mRNA (guanine-7-)-methyltransferase from vaccinia virions. Donor and acceptor substrate specificites (1976), J. Biol. Chem., 251, 7313-7321.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
viral nucleocapsid
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Vaccinia virus 19013
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Organism

Organism UniProt Comment Textmining
Vaccinia virus
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-
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dGTP + pp(5')RNA
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Vaccinia virus dG(5')ppp(5')RNA + diphosphate deoxyguanosine residue linked 5' through three phosphates to the 5' position of the terminal residue r
GTP + pp(5')RNA
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Vaccinia virus G(5')ppp(5')RNA + diphosphate guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue r
additional information specificity overview Vaccinia virus ?
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?
additional information lacks strict sequence specificity, homoribonucleotides containing purines are preferred, in presence of diphosphate the enzyme catalyzes the phosphorolysis of the dinucleoside triphosphate G(5')pp(5')A but not of m7(5')pp(5')A Vaccinia virus ?
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?