Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(R)-9-(2-phosphonomethoxypropyl)adenine | - |
Human immunodeficiency virus 1 | |
1,10-di-2',3'-dideoxy-3'-thiacytidine-decanoate | - |
Human immunodeficiency virus 1 | |
1,10-di-3'-azido-2',3'-dideoxythymidine-decanoate | - |
Human immunodeficiency virus 1 | |
1,10-di-3'-fluoro-2',3'-dideoxythymidine-decanoate | - |
Human immunodeficiency virus 1 | |
1,12-di-2',3'-dideoxy-3'-thiacytidine-dodecanoate | - |
Human immunodeficiency virus 1 | |
1,12-di-3'-azido-2',3'-dideoxythymidine-dodecanoate | - |
Human immunodeficiency virus 1 | |
1,12-di-3'-fluoro-2',3'-dideoxythymidine-dodecanoate | - |
Human immunodeficiency virus 1 | |
1,14-di-2',3'-dideoxy-3'-thiacytidine-tetradecanoate | - |
Human immunodeficiency virus 1 | |
1,14-di-3'-azido-2',3'-dideoxythymidine-tetradecanoate | - |
Human immunodeficiency virus 1 | |
1,14-di-3'-fluoro-2',3'-dideoxythymidine-tetradecanoate | - |
Human immunodeficiency virus 1 | |
1,4-di-2',3'-dideoxy-3'-thiacytidine-succinate | - |
Human immunodeficiency virus 1 | |
2',3'-didehydro-2',3'-dideoxythymidine | - |
Human immunodeficiency virus 1 | |
2',3'-dideoxy-3'-thiacytidine | - |
Human immunodeficiency virus 1 | |
2',3'-dideoxy-5-fluoro-3'-thiacytidine | - |
Human immunodeficiency virus 1 | |
2',3'-dideoxycytidine | - |
Human immunodeficiency virus 1 | |
3'-azido-2',3'-dideoxythymidine | - |
Human immunodeficiency virus 1 | |
3'-azido-3'-deoxythymidine | - |
Human immunodeficiency virus 1 | |
3'-fluoro-2',3'-dideoxythymidine | - |
Human immunodeficiency virus 1 | |
additional information | inhibitor structure-activity relationships, overview | Human immunodeficiency virus 1 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human immunodeficiency virus 1 | - |
- |
- |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00000076 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,14-di-3'-fluoro-2',3'-dideoxythymidine-tetradecanoate | |
0.00000097 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,12-di-3'-fluoro-2',3'-dideoxythymidine-dodecanoate | |
0.000001 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,10-di-3'-fluoro-2',3'-dideoxythymidine-decanoate | |
0.000002 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 3'-azido-2',3'-dideoxythymidine | |
0.000002 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 3'-fluoro-2',3'-dideoxythymidine | |
0.000002 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,12-di-3'-azido-2',3'-dideoxythymidine-dodecanoate | |
0.000003 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,14-di-3'-fluoro-2',3'-dideoxythymidine-tetradecanoate | |
0.000003 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,14-di-3'-azido-2',3'-dideoxythymidine-tetradecanoate | |
0.000003 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,14-di-2',3'-dideoxy-3'-thiacytidine-tetradecanoate | |
0.000003 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,14-di-3'-azido-2',3'-dideoxythymidine-tetradecanoate | |
0.000004 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,10-di-3'-fluoro-2',3'-dideoxythymidine-decanoate | |
0.000004 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,12-di-3'-fluoro-2',3'-dideoxythymidine-dodecanoate | |
0.000004 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,12-di-3'-azido-2',3'-dideoxythymidine-dodecanoate | |
0.000004 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,10-di-3'-azido-2',3'-dideoxythymidine-decanoate | |
0.000005 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,10-di-3'-azido-2',3'-dideoxythymidine-decanoate | |
0.000008 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 3'-azido-2',3'-dideoxythymidine | |
0.000009 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,12-di-2',3'-dideoxy-3'-thiacytidine-dodecanoate | |
0.00002 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 3'-fluoro-2',3'-dideoxythymidine | |
0.00002 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,12-di-2',3'-dideoxy-3'-thiacytidine-dodecanoate | |
0.00003 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,10-di-2',3'-dideoxy-3'-thiacytidine-decanoate | |
0.00003 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,14-di-2',3'-dideoxy-3'-thiacytidine-tetradecanoate | |
0.00006 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,10-di-2',3'-dideoxy-3'-thiacytidine-decanoate | |
0.00009 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 2',3'-dideoxy-3'-thiacytidine | |
0.00013 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,4-di-2',3'-dideoxy-3'-thiacytidine-succinate | |
0.00015 | - |
enzyme from HIV-1 US/92/727, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 1,4-di-2',3'-dideoxy-3'-thiacytidine-succinate | |
0.0002 | - |
enzyme from HIV-1 III B, pH and temperature not specified in the publication | Human immunodeficiency virus 1 | 2',3'-dideoxy-3'-thiacytidine |