Literature summary for 2.7.7.49 extracted from

Ma, X.; Liu, D.; Tang, H.; Wang, Y.; Wu, T.; Li, Y.; Yang, J.; Yang, J.; Sun, S.; Zhang, F.
Purification and characterization of a novel antifungal protein with antiproliferation and anti-HIV-1 reverse transcriptase activities from Peganum harmala seeds (2013), Acta Biochim. Biophys. Sin. (Shanghai), 45, 87-94.

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Inhibitors

Inhibitors	Comment	Organism	Structure
PHP protein	a dimeric 16 kDa antifungal protein, isolated from the seeds of Peganum harmala by cationic exchange chromatography and gel filtration, inhibitor isoelectric point is about 8.4. Inhibits the viral polymerase to 69.1%. The protein has also inhibitory effect on cell proliferation and fungal growth, overview	Human immunodeficiency virus 1

Organism

Organism	UniProt	Comment	Textmining
Human immunodeficiency virus 1	-	-	-

Synonyms

Synonyms	Comment	Organism
HIV-1 reverse transcriptase	-	Human immunodeficiency virus 1

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.00126	-	pH and temperature not specified in the publication	Human immunodeficiency virus 1	PHP protein

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Release 2023.1 (January 2023)