Literature summary for 2.7.7.49 extracted from

Birkus, G.; Kutty, N.; He, G.X.; Mulato, A.; Lee, W.; McDermott, M.; Cihlar, T.
Activation of 9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino] phenoxyphosphinyl]-methoxy]propyl]adenine (GS-7340) and other tenofovir phosphonoamidate prodrugs by human proteases (2008), Mol. Pharmacol., 74, 92-100.

Search for more literature for 2.7.7.49

Inhibitors

Inhibitors	Comment	Organism	Structure
Tenofovir	9-[(2-phosphonomethoxy)propyl]adenine	Human Immunodeficiency Virus

Organism

Organism	UniProt	Comment	Textmining
Human Immunodeficiency Virus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
deoxynucleoside triphosphate + DNAn	-	Human Immunodeficiency Virus	diphosphate + DNAn+1	-	?

Synonyms

Synonyms	Comment	Organism
reverse transcriptase	-	Human Immunodeficiency Virus

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Release 2023.1 (January 2023)