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Literature summary for 2.7.7.49 extracted from
- Fidelity and processivity of reverse transcription by the human mitochondrial DNA polymerase (2007), J. Biol. Chem., 44, 31982-31989.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | the reverse transcriptase activity of DNA polymerase gamma is not likely to contribute significantly to the biology of mitochondrial DNA replication | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the reverse transcriptase activity of DNA polymerase gamma is not likely to contribute significantly to the biology of mitochondrial DNA replication | Homo sapiens | ? | - |
? | |
| additional information | the reverse transcriptase activity of DNA polymerase gamma: in comparison with the kinetic parameters observed with a DNA template, the rate of correct deoxynucleotide incorporation is reduced 25fold, whereas the dissociation constant for nucleotide binding is increased 4fold | Homo sapiens | ? | - |
? | |
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