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Literature summary for 2.7.7.48 extracted from

  • Chand, G.B.; Banerjee, A.; Azad, G.K.
    Identification of novel mutations in RNA-dependent RNA polymerases of SARS-CoV-2 and their implications on its protein structure (2020), PeerJ, 8, e9492 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.48

Protein Variants

Protein Variants Comment Organism
A185V mutation causes change in secondary structure Severe acute respiratory syndrome coronavirus 2
A466V mutation has no effect on secondary structure Severe acute respiratory syndrome coronavirus 2
A97V mutation causes change in secondary structure Severe acute respiratory syndrome coronavirus 2
I201L mutation has no effect on secondary structure Severe acute respiratory syndrome coronavirus 2
L329I mutation has no effect on secondary structure Severe acute respiratory syndrome coronavirus 2
P323L mutation causes change in secondary structure Severe acute respiratory syndrome coronavirus 2
V880I mutation has no effect on secondary structure Severe acute respiratory syndrome coronavirus 2

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nucleoside triphosphate + RNAn Severe acute respiratory syndrome coronavirus 2
-
 diphosphate + RNAn+1
-
 ?

Organism

Organism UniProt Comment Textmining
Severe acute respiratory syndrome coronavirus 2 P0DTD1 replicase polyprotein 1ab; SARS-CoV-2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside triphosphate + RNAn
-
 Severe acute respiratory syndrome coronavirus 2 diphosphate + RNAn+1
-
 ?

Synonyms

Synonyms Comment Organism
RDRP
-
 Severe acute respiratory syndrome coronavirus 2
RNA-dependent RNA polymerase
-
 Severe acute respiratory syndrome coronavirus 2