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Literature summary for 2.7.7.48 extracted from

  • Babadaei, M.M.N.; Hasan, A.; Vahdani, Y.; Bloukh, S.H.; Sharifi, M.; Kachooei, E.; Haghighat, S.; Falahati, M.
    Development of remdesivir repositioning as a nucleotide analog against COVID-19 RNA dependent RNA polymerase (2020), J. Biomol. Struct. Dyn., 2020, 1-9 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
remdesivir
-
Severe acute respiratory syndrome coronavirus 2

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nucleoside triphosphate + RNAn Severe acute respiratory syndrome coronavirus 2
-
diphosphate + RNAn+1
-
?

Organism

Organism UniProt Comment Textmining
Severe acute respiratory syndrome coronavirus 2 P0DTD1 replicase polyprotein 1ab; SARS-CoV-2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside triphosphate + RNAn
-
Severe acute respiratory syndrome coronavirus 2 diphosphate + RNAn+1
-
?

Synonyms

Synonyms Comment Organism
RDRP
-
Severe acute respiratory syndrome coronavirus 2
RNA-dependent RNA polymerase
-
Severe acute respiratory syndrome coronavirus 2