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Literature summary for 2.7.7.48 extracted from

  • Kidmose, R.T.; Vasiliev, N.N.; Chetverin, A.B.; Andersen, G.R.; Knudsen, C.R.
    Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins (2010), Proc. Natl. Acad. Sci. USA, 107, 10884-10889.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Escherichia coli
expression in Escherichia coli Qubevirus durum

Crystallization (Commentary)

Crystallization (Comment) Organism
structure of Qbeta replicase complex, to 2.5 A resolution. Qbeta replicase is composed of the bacteriophage Qbeta catalytic beta-subunit as well as the Escherichia coli host translation elongation factors EF-Tu and EF-Ts. The basic catalytic machinery in the viral subunit appears similar to other RNA-dependent RNA polymerases, while a C-terminal region of the beta-subunit engages in extensive interactions with EF-Tu and may contribute to the separation of the transient duplex formed between the template and the nascent product to allow exponential amplification of the phage genome Escherichia coli
structure of Qbeta replicase complex, to 2.5 A resolution. Qbeta replicase is composed of the bacteriophage Qbeta catalytic beta-subunit as well as the Escherichia coli host translation elongation factors EF-Tu and EF-Ts. The basic catalytic machinery in the viral subunit appears similar to other RNA-dependent RNA polymerases, while a C-terminal region of the beta-subunit engages in extensive interactions with EF-Tu and may contribute to the separation of the transient duplex formed between the template and the nascent product to allow exponential amplification of the phage genome Qubevirus durum

Organism

Organism UniProt Comment Textmining
Escherichia coli
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-
-
Qubevirus durum Q8LTE0
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-

Subunits

Subunits Comment Organism
More Qbeta replicase is composed of the bacteriophage Qbeta catalytic beta-subunit as well as the Escherichia coli host translation elongation factors EF-Tu and EF-Ts Escherichia coli
More Qbeta replicase is composed of the bacteriophage Qbeta catalytic beta-subunit as well as the Escherichia coli host translation elongation factors EF-Tu and EF-Ts Qubevirus durum