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Literature summary for 2.7.7.48 extracted from

  • Ying, X.B.; Dong, L.; Zhu, H.; Duan, C.G.; Du, Q.S.; Lv, D.Q.; Fang, Y.Y.; Garcia, J.A.; Fang, R.X.; Guo, H.S.
    RNA-dependent RNA polymerase 1 from Nicotiana tabacum suppresses RNA silencing and enhances viral infection in Nicotiana benthamiana (2010), Plant Cell, 22, 1358-1372.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Nicotiana tabacum
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General Information

General Information Comment Organism
physiological function Nicotiana benthamiana transformed with isoform RDR1 from Nicotiana tabacum exhibits hypersusceptibility to plum pox potyvirus and other viruses, resembling RDR6-silenced Nicotiana benthamiana. Nicotiana tabacum-RDR1 possesses silencing suppression activity and does not interfere with isoform RDR6-dependent siRNA accumulation but turns out to suppress RDR6-dependent sense-transgenes Isoform RDR1 might have a dual role, contributing, on one hand, to salicylic acid-mediated antiviral defense, and suppressing, on the other hand, the RDR6-mediated antiviral RNA silencing Nicotiana tabacum