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Literature summary for 2.7.7.45 extracted from

  • Liu, J.J.; McLennan, A.G.
    Purification and properties of GTP:GTP guanylyltransferase from embryos of the brine shrimp Artemia (1994), Biochem. Soc. Trans., 22, 219S.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.7
-
GTP
-
Artemia sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
80000
-
2 * 142000, alpha + 2 * 80000, beta, SDS-PAGE Artemia sp.
142000
-
2 * 142000, alpha + 2 * 80000, beta, SDS-PAGE Artemia sp.
480000
-
gel filtration Artemia sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + GTP Artemia sp.
-
diphosphate + P1,P4-bis(5'-guanosyl)tetraphosphate
-
r

Organism

Organism UniProt Comment Textmining
Artemia sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Artemia sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dGTP + dGTP 96% of the activity with GTP as second substrate Artemia sp. P1,P4-bis(5'-(2'-deoxyguanosyl) tetraphosphate + diphosphate
-
r
GTP + GTP
-
Artemia sp. P1,P4-bis(5'-guanosyl)tetraphosphate + diphosphate i.e. GP4G r
GTP + GTP
-
Artemia sp. diphosphate + P1,P4-bis(5'-guanosyl)tetraphosphate
-
r
GTP + ITP
-
Artemia sp. GppppI + diphosphate
-
r
GTP + P1,P4-bis(5'-guanosyl)tetraphosphate
-
Artemia sp. ?
-
r
GTP + XTP
-
Artemia sp. GppppX + diphosphate
-
r

Subunits

Subunits Comment Organism
tetramer 2 * 142000, alpha + 2 * 80000, beta, SDS-PAGE Artemia sp.

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.2
-
GTP
-
Artemia sp.