Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + sn-glycerol 3-phosphate | Enterococcus faecalis | - |
diphosphate + CDP-glycerol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Enterococcus faecalis | Q836D9 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + sn-glycerol 3-phosphate | - |
Enterococcus faecalis | diphosphate + CDP-glycerol | - |
? | |
additional information | using an assay method for determination of the catalytic activity measuring the production of radiolabeled CDP-glycerol from 14C-labeled sn-glycerol 3-phosphate, and separation of non-radioactive CDP-glycerol from CTP by C18 reverse phase HPLC with a mobile phase of 0.1 M ammonium bicarbonate (98%) and acetonitrile (2%) at pH 7.4 | Enterococcus faecalis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cytidylyltransferase | - |
Enterococcus faecalis |
GCT | - |
Enterococcus faecalis |
glycerol 3-phosphate cytidylyltransferase | - |
Enterococcus faecalis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Enterococcus faecalis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Enterococcus faecalis |
General Information | Comment | Organism |
---|---|---|
evolution | the enzyme is a member of the cytidylyltransferase family of enzymes that utilize cytidine 5'-triphosphate (CTP) to synthesize molecules that are typically precursors to membrane phospholipids | Enterococcus faecalis |
metabolism | the enzyme catalyzes conversion of phosphocholine and CTP to cytidine diphosphocholine (CDP-choline), a step critical for synthesis of the membrane phospholipid phosphatidylcholine | Enterococcus faecalis |