Literature summary for 2.7.7.3 extracted from

Cheng, C.S.; Chen, C.H.; Luo, Y.C.; Chen, W.T.; Chang, S.Y.; Lyu, P.C.; Kao, M.C.; Yin, H.S.
Crystal structure and biophysical characterisation of Helicobacter pylori phosphopantetheine adenylyltransferase (2011), Biochem. Biophys. Res. Commun., 408, 356-361.

Search for more literature for 2.7.7.3

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Helicobacter pylori

Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging drop vapor diffusion method, using 0.1 M TrisHCl, pH 7.0, containing 2.0 M (NH4)2SO4 and 0.2 M Li2SO4	Helicobacter pylori

Inhibitors

Inhibitors	Comment	Organism	Structure
coenzyme A	feedback inhibition	Helicobacter pylori

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
19701	-	6 * 19701, MALDI-TOF mass spectrometry	Helicobacter pylori
20000	-	6 * 20000, SDS-PAGE	Helicobacter pylori
128600	-	analytical ultracentrifugation	Helicobacter pylori

Organism

Organism	UniProt	Comment	Textmining
Helicobacter pylori	O26010	-	-

Purification (Commentary)

Purification (Comment)	Organism
Co2 + affinity column chromatography	Helicobacter pylori

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + pantetheine 4'-phosphate	-	Helicobacter pylori	diphosphate + 3'-dephospho-CoA	-	?

Subunits

Subunits	Comment	Organism
homohexamer	6 * 20000, SDS-PAGE	Helicobacter pylori
homohexamer	6 * 19701, MALDI-TOF mass spectrometry	Helicobacter pylori

Synonyms

Synonyms	Comment	Organism
phosphopantetheine adenylyltransferase	-	Helicobacter pylori
PPAT	-	Helicobacter pylori

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Release 2023.1 (January 2023)