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Literature summary for 2.7.7.27 extracted from

  • Chen, L.S.; Qi, Y.P.
    Dithiothreitol decreases in vitro activity of ADP-glucose pyrophosphorylase from leaves of apple (Malus domestica Borkh.) and many other plant species (2007), Phytochem. Anal., 18, 300-305.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
3-phosphoglycerate in leaves 2-3fold, DTT decreases the activation Solanum lycopersicum
3-phosphoglycerate in leaves 2-3fold, DTT highly decreases the activation Glycine max
3-phosphoglycerate in leaves 2fold, DTT abolishes the activation at 5 mM Triticum aestivum
3-phosphoglycerate in leaves 2fold, DTT abolishes the activation at 5 mM Arabidopsis thaliana
3-phosphoglycerate in leaves 2fold, DTT decreases the activation Hordeum vulgare
3-phosphoglycerate in leaves 30fold, DTT abolishes the activation at 1-5 mM Spinacia oleracea
3-phosphoglycerate in leaves and tubers 1.4-3.8fold, DTT decreases the activation, overview Solanum tuberosum
3-phosphoglycerate slight activation, DTT abolishes the activation Sorghum sp.
dithiothreitol in absence of 3-phosphoglycerate, increase of acitivity for enzyme from tuber, no effect on enzyme from leaf Solanum tuberosum

Inhibitors

Inhibitors Comment Organism Structure
dithiothreitol in presence of 3-phophoglycerate, decrease of acitivity Arabidopsis thaliana
dithiothreitol inhibition is prevented by pre- or by coincubation with 3-phophoglycerate, but incubation of already inhibited enzyme with 3-phophoglycerate may not reverse the inhibition Malus domestica
dithiothreitol in presence of 3-phophoglycerate, decrease of acitivity for enzyme from tuber Solanum tuberosum
DTT 3-phosphoglycerate protects completely when added before the inhibition, but does not affect the enzyme activity after inhibition by DTT takes place Malus domestica

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Triticum aestivum
Mg2+
-
Hordeum vulgare
Mg2+
-
Spinacia oleracea
Mg2+
-
Solanum tuberosum
Mg2+
-
Glycine max
Mg2+
-
Arabidopsis thaliana
Mg2+
-
Solanum lycopersicum
Mg2+
-
Sorghum sp.
Mg2+
-
Malus domestica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + alpha-D-glucose 1-phosphate Triticum aestivum
-
ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate Hordeum vulgare
-
ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate Spinacia oleracea
-
ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate Solanum tuberosum
-
ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate Glycine max
-
ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate Arabidopsis thaliana
-
ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate Solanum lycopersicum
-
ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate Sorghum sp.
-
ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate Malus domestica
-
ADP-D-glucose + diphosphate
-
r

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-
Glycine max
-
-
-
Hordeum vulgare
-
-
-
Malus domestica
-
-
-
Solanum lycopersicum
-
-
-
Solanum tuberosum
-
-
-
Sorghum sp.
-
-
-
Spinacia oleracea
-
-
-
Triticum aestivum
-
-
-

Renatured (Commentary)

Renatured (Comment) Organism
inhibition of enzyme by dithiothreitol is prevented by pre- or by coincubation with 3-phophoglycerate, but incubation of already inhibited enzyme with 3-phophoglycerate may not reverse the inhibition Solanum tuberosum
inhibition of enzyme by dithiothreitol is prevented by pre- or by coincubation with 3-phophoglycerate, but incubation of already inhibited enzyme with 3-phophoglycerate may not reverse the inhibition Arabidopsis thaliana
inhibition of enzyme by dithiothreitol is prevented by pre- or by coincubation with 3-phophoglycerate, but incubation of already inhibited enzyme with 3-phophoglycerate may not reverse the inhibition Malus domestica

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Triticum aestivum
-
leaf
-
Hordeum vulgare
-
leaf
-
Spinacia oleracea
-
leaf
-
Solanum tuberosum
-
leaf
-
Glycine max
-
leaf
-
Arabidopsis thaliana
-
leaf
-
Solanum lycopersicum
-
leaf
-
Sorghum sp.
-
leaf
-
Malus domestica
-
tuber
-
Solanum tuberosum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + alpha-D-glucose 1-phosphate
-
Triticum aestivum ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate
-
Hordeum vulgare ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate
-
Spinacia oleracea ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate
-
Solanum tuberosum ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate
-
Glycine max ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate
-
Arabidopsis thaliana ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate
-
Solanum lycopersicum ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate
-
Sorghum sp. ADP-D-glucose + diphosphate
-
r
ATP + alpha-D-glucose 1-phosphate
-
Malus domestica ADP-D-glucose + diphosphate
-
r

Synonyms

Synonyms Comment Organism
ADP-glucose pyrophosphorylase
-
Triticum aestivum
ADP-glucose pyrophosphorylase
-
Hordeum vulgare
ADP-glucose pyrophosphorylase
-
Spinacia oleracea
ADP-glucose pyrophosphorylase
-
Solanum tuberosum
ADP-glucose pyrophosphorylase
-
Glycine max
ADP-glucose pyrophosphorylase
-
Arabidopsis thaliana
ADP-glucose pyrophosphorylase
-
Solanum lycopersicum
ADP-glucose pyrophosphorylase
-
Sorghum sp.
ADP-glucose pyrophosphorylase
-
Malus domestica
AGPase
-
Triticum aestivum
AGPase
-
Hordeum vulgare
AGPase
-
Spinacia oleracea
AGPase
-
Solanum tuberosum
AGPase
-
Glycine max
AGPase
-
Arabidopsis thaliana
AGPase
-
Solanum lycopersicum
AGPase
-
Sorghum sp.
AGPase
-
Malus domestica

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Triticum aestivum
37
-
assay at Hordeum vulgare
37
-
assay at Spinacia oleracea
37
-
assay at Solanum tuberosum
37
-
assay at Glycine max
37
-
assay at Arabidopsis thaliana
37
-
assay at Solanum lycopersicum
37
-
assay at Sorghum sp.
37
-
assay at Malus domestica

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
assay at Triticum aestivum
8
-
assay at Hordeum vulgare
8
-
assay at Spinacia oleracea
8
-
assay at Solanum tuberosum
8
-
assay at Glycine max
8
-
assay at Arabidopsis thaliana
8
-
assay at Solanum lycopersicum
8
-
assay at Sorghum sp.
8
-
assay at Malus domestica