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Literature summary for 2.7.7.24 extracted from

  • Li, S.; Wang, H.; Jin, G.; Chen, Z.; Gu, G.
    Exploring the broad nucleotide triphosphate and sugar-1-phosphate specificity of thymidylyltransferase Cps23FL from Streptococcus pneumonia serotype 23F (2020), RSC Adv., 10, 30110-30114 .
No PubMed abstract available
Search for more literature for 2.7.7.24

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dTTP + alpha-D-glucose 1-phosphate Streptococcus pneumoniae
-
 diphosphate + dTDP-alpha-D-glucose
-
 ?

Organism

Organism UniProt Comment Textmining
Streptococcus pneumoniae
-
 serotype 23F
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + alpha-D-glucose 1-phosphate 13% yield with 0.006 mM enzyme, 78% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + ADP-alpha-D-glucose
-
 ?
dATP + alpha-D-glucosamine 1-phosphate 21% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dADP-alpha-D-glucosamine
-
 ?
dCTP + alpha-D-glucose 1-phosphate 35% yield with 0.006 mM enzyme, 87% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dCDP-alpha-D-glucose
-
 ?
dGTP + alpha-D-glucose 1-phosphate 53% yield with 0.006 mM enzyme, 89% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dGDP-alpha-D-glucose
-
 ?
dTTP + alpha-D-galactosamine 1-phosphate 5% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dTDP-alpha-D-galactosamine
-
 ?
dTTP + alpha-D-galactose 1-phosphate 91% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dTDP-alpha-D-galactose
-
 ?
dTTP + alpha-D-glucosamine 1-phosphate 71% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dTDP-alpha-D-glucosamine
-
 ?
dTTP + alpha-D-glucose 1-phosphate
-
 Streptococcus pneumoniae diphosphate + dTDP-alpha-D-glucose
-
 ?
dTTP + alpha-D-glucose 1-phosphate 86% yield with 0.006 mM enzyme, 93% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dTDP-alpha-D-glucose
-
 ?
dTTP + alpha-D-mannose 1-phosphate 88% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dTDP-alpha-D-mannose
-
 ?
dUTP + alpha-D-galactose 1-phosphate 83% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dUDP-alpha-D-galactose
-
 ?
dUTP + alpha-D-glucose 1-phosphate 88% yield with 0.006 mM enzyme, 95% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + dUDP-alpha-D-glucose
-
 ?
GTP + alpha-D-glucose 1-phosphate no product yield with 0.006 mM enzyme, 91% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + GDP-alpha-D-glucose
-
 ?
GTP + alpha-D-mannose 1-phosphate 13% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + GDP-alpha-D-mannose
-
 ?
additional information no activity with alpha-D-galacturonic acid 1-phosphate Streptococcus pneumoniae ?
-
-
UTP + alpha-D-galactose 1-phosphate 86% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + UDP-alpha-D-galactose
-
 ?
UTP + alpha-D-glucosamine 1-phosphate 12% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + UDP-alpha-D-glucosamine
-
 ?
UTP + alpha-D-glucose 1-phosphate 40% yield with 0.006 mM enzyme, 94% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + UDP-alpha-D-glucose
-
 ?
UTP + alpha-D-mannose 1-phosphate 78% yield with 0.06 mM enzyme Streptococcus pneumoniae diphosphate + UDP-alpha-D-mannose
-
 ?

Synonyms

Synonyms Comment Organism
Cps23FL
-
 Streptococcus pneumoniae
glucose-1-phosphate thymidylyltransferase
-
 Streptococcus pneumoniae