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Literature summary for 2.7.7.23 extracted from

  • Arakane, Y.; Baguinon, M.C.; Jasrapuria, S.; Chaudhari, S.; Doyungan, A.; Kramer, K.J.; Muthukrishnan, S.; Beeman, R.W.
    Both UDP N-acetylglucosamine pyrophosphorylases of Tribolium castaneum are critical for molting, survival and fecundity (2011), Insect Biochem. Mol. Biol., 41, 42-50.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Tribolium castaneum D2KLJ1 isoform UAP1
-
Tribolium castaneum D2KLJ2 isoform UAP2
-

Synonyms

Synonyms Comment Organism
UAP1
-
Tribolium castaneum
UAP2
-
Tribolium castaneum

General Information

General Information Comment Organism
physiological function down-regulation of transcripts by RNA interference prevents larval growth or results in pupal paralysis, depending on time of injection of double-stranded RNAs. Down-regulation of transcripts at the mature adult stage results in cessation of oviposition in females, as well as fat body depletion and eventual death in both sexes Tribolium castaneum
physiological function down-regulation of transcripts by RNA interference results for isoform UAP1 in specific arrest at the larval-larval, larval-pupal or pupal-adult molts, depending on time of injection of double-stranded RNAs, loss of structural integrity and chitin staining and loss of peritrophic matrix-associated chitin. Down-regulation of transcripts at the mature adult stage results in cessation of oviposition in females, as well as fat body depletion and eventual death in both sexes Tribolium castaneum