Literature summary for 2.7.7.22 extracted from

Empadinhas, N.; Marugg, J.D.; Borges, N.; Santos, H.; Da Costa, M.S.
Pathway for the synthesis of mannosylglycerate in the hyperthermophilic archaeon Pyrococcus horikoshii. Biochemical and genetic characterization of key enzymes (2001), J. Biol. Chem., 276, 43580-43588.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
GDPmannose + phosphate	Pyrococcus horikoshii	reverse reaction involved in synthesis of the compatible solute alpha-mannosylglycerate	GDP + mannose 1-phosphate	-	r

Organism

Organism	UniProt	Comment	Textmining
Pyrococcus horikoshii	O58649	hyperthermophilic archeon	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GDPmannose + phosphate	-	Pyrococcus horikoshii	GDP + mannose 1-phosphate	-	r
GDPmannose + phosphate	reverse reaction involved in synthesis of the compatible solute alpha-mannosylglycerate	Pyrococcus horikoshii	GDP + mannose 1-phosphate	-	r

Synonyms

Synonyms	Comment	Organism
More	bifunctional enzyme, phosphomannose isomerase activity as well as mannose 1-phosphate guanylyltransferase activity	Pyrococcus horikoshii

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Release 2023.1 (January 2023)