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Literature summary for 2.7.7.19 extracted from

  • Koch, H.; Raabe, M.; Urlaub, H.; Bindereif, A.; Preusser, C.
    The polyadenylation complex of Trypanosoma brucei: Characterization of the functional poly(A) polymerase (2016), RNA Biol., 13, 221-231.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm gene product of Tb927.3.3160 localizes mainly in the cytoplasm and appears not to be functional in general 3' end processing of mRNA Trypanosoma brucei brucei 5737
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nucleus gene product of Tb927.7.3780 is the major functional, nuclear-localized enzyme in trypanosomes Trypanosoma brucei brucei 5634
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Organism

Organism UniProt Comment Textmining
Trypanosoma brucei brucei Q57WJ3
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Trypanosoma brucei brucei Q57ZJ6
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Trypanosoma brucei brucei 927 / 4 GUTat10.1 / TREU927 Q57WJ3
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Trypanosoma brucei brucei 927 / 4 GUTat10.1 / TREU927 Q57ZJ6
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Synonyms

Synonyms Comment Organism
Tb927.3.3160
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Trypanosoma brucei brucei
Tb927.7.3780
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Trypanosoma brucei brucei

General Information

General Information Comment Organism
physiological function the trypanosome polyadenylation complex includes homologues to all four cleavage and polyadenylation specificity factor subunits, Fip1, CstF50/64, and Symplekin. Most of these factors are essential for growth and required for both in vivo polyadenylation and trans splicing Trypanosoma brucei brucei