Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | O17087 | - |
- |
General Information | Comment | Organism |
---|---|---|
physiological function | removal of either isoform GLD-2 or RNA-binding protein RNP-8 results in shortened poly(A) tails and lowers abundance of four target-mRNAs, i.e. oma-2, egg-1, pup-2, andtra-2. GLD-2 depletion also lowers the abundance of most GLD-2/RNP-8 putative target-mRNAs when assayed on microarrays. The GLD-2/RNP-8 complex is a broad-spectrum regulator of the oogenesis program that acts within an RNA regulatory network to specify and produce fully functional oocytes | Caenorhabditis elegans |