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Literature summary for 2.7.7.19 extracted from
- Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues (2010), Biochem. Pharmacol., 79, 669-677.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | P25500 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + RNA primer | in absence of ATP: no activity with 8-Cl-ATP, and 8-amino-ATP results in chain termination, in presence of ATP: polyadenylation of the primer is blocked (inhibited) by 8-amino-ATP and 8-Cl-ATP | Bos taurus | diphosphate + RNA primer-A | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| poly(A) polymerase II | - |
Bos taurus |
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Release 2023.1 (January 2023)
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