Literature summary for 2.7.7.19 extracted from

Mellman, D.L.; Gonzales, M.L.; Song, C.; Barlow, C.A.; Wang, P.; Kendziorski, C.; Anderson, R.A.
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs (2008), Nature, 451, 1013-1017.

Search for more literature for 2.7.7.19

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	other phosphoinositides besides phosphatidylinositol 4,5-bisphosphate do not affect Star-PAP activity, and no phosphoinositide has an effect on PAPalpha activity	Saccharomyces cerevisiae
phosphatidylinositol 4,5-bisphosphate	in the presence of 50 mM phosphatidylinositol 4,5-bisphosphate Star-PAP activity is markedly stimulated	Saccharomyces cerevisiae

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in HEK-293 cells	Saccharomyces cerevisiae

Inhibitors

Inhibitors	Comment	Organism	Structure
Cordycepin triphosphate	5.0 mM	Saccharomyces cerevisiae

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
nucleus	-	Saccharomyces cerevisiae	5634	-

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + RNA	-	Saccharomyces cerevisiae	diphosphate + RNA(A)n	-	?

Synonyms

Synonyms	Comment	Organism
nuclear speckle targeted PIPKIalpha regulated-poly(A) polymerase	-	Saccharomyces cerevisiae
PAPalpha	-	Saccharomyces cerevisiae
poly(A) polymerase	-	Saccharomyces cerevisiae
Star-PAP	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)