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Literature summary for 2.7.7.19 extracted from

  • Rissland, O.S.; Mikulasova, A.; Norbury, C.J.
    Efficient RNA polyuridylation by noncanonical poly(A) polymerases (2007), Mol. Cell. Biol., 27, 3612-3624.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.19

Cloned(Commentary)

Cloned (Comment) Organism
expressed in 293T cells Homo sapiens
expressed in Escherichia coli BL21(DE3) pLysS cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + RNA Homo sapiens
-
 diphosphate + RNA(A)n
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
native tandem affinity column chromatography Homo sapiens
Sepharose column chromatography Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + RNA
-
 Homo sapiens diphosphate + RNA(A)n
-
 ?
ATP + RNA Hs2 complexes have very little PAP activity, Hs2 also displays efficient poly(U) polymerase activity Homo sapiens diphosphate + RNA(A)n
-
 ?
UTP + RNA recombinant Cid1 shows a preference for UTP over ATP, the poly(U) polymerase activity of recombinant Cid1 out-competes its PAP activity under physiologically relevant conditions Homo sapiens diphosphate + RNA(U)n
-
 ?

Synonyms

Synonyms Comment Organism
Cid1 putative cytoplasmic PAP, in addition to having PAP activity, Cid1 possesses substantial poly(U) polymerase activity Homo sapiens
Hs2 contains two PAP-associated domains and two nucleotidyl transferase motifs Homo sapiens
PAP
-
 Homo sapiens
poly(A) polymerase
-
 Homo sapiens
ZCCHC6
-
 Homo sapiens